A new paper titled ‘Astrocyte 3D culture and bioprinting using peptide functionalized hyaluronan hydrogels‘ was published in Science and Technology of Advanced Materials today.
This work highlights the development of peptide functionalized hyaluronan hydrogels for bioprinting. The study utilized neuroblastoma (SH-SY5Y) and glioblastoma (U87) cell lines and human fetal primary astrocytes (FPA) with a modular hyaluronan-based hydrogel system. It was observed that FPA had a higher degree of interaction with the hyaluronan-based gels compared to the cell lines. These engineered hydrogels enable the possibilities to bioprint, culture and maintain FPA and can thus facilitate the development of more elaborate neural and astrocytic tissue and disease models.